Nomifensine

CHEMBL273575 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

238.3 g/mol

LogP

2.6

Phase

4

A norepinephrine–dopamine reuptake inhibitor that was used as an antidepressant but was withdrawn worldwide due to a high incidence of immune hemolytic anemia. It was effective in treating depression but carried unacceptable safety risks.

分子量

238.3300 g/mol

LogP

2.60

TPSA

29.30 Å²

リピンスキーの五則

適合

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

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SMILES

CN1Cc2c(N)cccc2C(c2ccccc2)C1

InChI

InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3

Molecular Formula

C16H18N2

HBD / HBA

1 / 2

回転可能結合数

1

重原子数

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

A norepinephrine–dopamine reuptake inhibitor that was used as an antidepressant but was withdrawn worldwide due to a high incidence of immune hemolytic anemia. It was effective in treating depression but carried unacceptable safety risks.

Yes, Nomifensine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL273575. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4528. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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構造

クイックデータ

分子式: C16H18N2

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医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.