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Potassium Nitrate

CHEMBL1644029 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
101.1 g/mol
LogP
—
Phase
4

Potassium nitrate is an inorganic salt that can act as a nitrate donor, being metabolized to nitrite and subsequently to nitric oxide, which causes vasodilation of blood vessels through activation of soluble guanylate cyclase and smooth muscle relaxation. It has been used historically as an antihypertensive and antianginal agent, and topically in desensitizing toothpastes for dentinal hypersensitivity through occlusion of dentinal tubules.

分子量

101.1030 g/mol

TPSA

62.90 Ų

治療領域

Cardiovascular Disease Pain Management Obesity Hypertension Chronic Pain Heart Failure

作用機序

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=[N+]([O-])[O-].[K+]

                

                

                
                

                    
InChI

                    
InChI=1S/K.NO3/c;2-1(3)4/q+1;-1

                

                

                

                    
                    

                        
Molecular Formula

                        
KNO3

                    

                    
                    

                        
HBD / HBA

                        
- / 3

                    

                    
                    

                        
回転可能結合数

                        
0

                    

                    
                    
                    

                        
重原子数

                        
5

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
Potassium nitrate is an inorganic salt that can act as a nitrate donor, being metabolized to nitrite and subsequently to nitric oxide, which causes vasodilation of blood vessels through activation of soluble guanylate cyclase and smooth muscle relaxation. It has been used historically as an antihypertensive and antianginal agent, and topically in desensitizing toothpastes for dentinal hypersensitivity through occlusion of dentinal tubules.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Potassium Nitrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1644029.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 24434.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.