Remimazolam
Remimazolam is an ultra-short-acting benzodiazepine sedative that enhances GABA-A receptor-mediated inhibitory neurotransmission to produce dose-dependent sedation and anxiolysis, and is rapidly hydrolyzed by tissue esterases to an inactive metabolite, providing predictable and titratable sedation with rapid recovery. It is approved for procedural sedation and induction and maintenance of general anesthesia.
分子量
439.3000 g/mol
LogP
3.40
TPSA
69.40 Ų
リピンスキーの五則
適合
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
COC(=O)CC[C@@H]1N=C(c2ccccn2)c2cc(Br)ccc2-n2c(C)cnc21
InChI
InChI=1S/C21H19BrN4O2/c1-13-12-24-21-17(7-9-19(27)28-2)25-20(16-5-3-4-10-23-16)15-11-14(22)6-8-18(15)26(13)21/h3-6,8,10-12,17H,7,9H2,1-2H3/t17-/m0/s1
Molecular Formula
C21H19BrN4O2
HBD / HBA
- / 5
回転可能結合数
5
重原子数
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Remimazolam is an ultra-short-acting benzodiazepine sedative that enhances GABA-A receptor-mediated inhibitory neurotransmission to produce dose-dependent sedation and anxiolysis, and is rapidly hydrolyzed by tissue esterases to an inactive metabolite, providing predictable and titratable sedation with rapid recovery. It is approved for procedural sedation and induction and maintenance of general anesthesia.
Yes, Remimazolam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297526. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9867812. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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