Rimabotulinumtoxinb
Rimabotulinumtoxin B is a botulinum neurotoxin type B that cleaves the vesicle-associated membrane protein (VAMP/synaptobrevin) component of the SNARE complex at peripheral cholinergic nerve terminals, preventing acetylcholine release and causing localized, temporary muscle paralysis or glandular secretion reduction. It is approved for the treatment of cervical dystonia and hyperhidrosis, and is used off-label for spasticity in multiple sclerosis and post-stroke conditions.
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Rimabotulinumtoxin B is a botulinum neurotoxin type B that cleaves the vesicle-associated membrane protein (VAMP/synaptobrevin) component of the SNARE complex at peripheral cholinergic nerve terminals, preventing acetylcholine release and causing localized, temporary muscle paralysis or glandular secretion reduction. It is approved for the treatment of cervical dystonia and hyperhidrosis, and is used off-label for spasticity in multiple sclerosis and post-stroke conditions.
Yes, Rimabotulinumtoxinb is an approved drug. It has reached clinical phase 4. It is classified as a Protein.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201569. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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