Romidepsin

CHEMBL343448 Phase 4 承認済み Protein
Half-Life
Bioavailability
Protein Binding
Molecular Weight
540.7 g/mol
LogP
2.2
Phase
4

A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.

分子量

540.7000 g/mol

LogP

2.20

TPSA

193.00 Ų

リピンスキーの五則

適合

治療領域

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

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SMILES

C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O

InChI

InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1

Molecular Formula

C24H36N4O6S2

HBD / HBA

4 / 8

回転可能結合数

2

重原子数

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.

Yes, Romidepsin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL343448. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5352062. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.