Secnidazole

CHEMBL498847 Phase 4 承認済み Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

185.2 g/mol

LogP

0.2

Phase

4

Secnidazole is a 5-nitroimidazole antiprotozoal and antibacterial agent with a longer half-life than metronidazole, approved for single-dose treatment of bacterial vaginosis and trichomoniasis. Its active nitroimidazole moiety is reduced intracellularly to cytotoxic intermediates that disrupt DNA integrity in anaerobic bacteria and parasites. Single-dose oral administration improves adherence compared to multi-day regimens.

分子量

185.1800 g/mol

LogP

0.20

TPSA

83.90 Å²

リピンスキーの五則

適合

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D構造

SVG PNG

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Embed this structure

SMILES

Cc1ncc([N+](=O)[O-])n1CC(C)O

InChI

InChI=1S/C7H11N3O3/c1-5(11)4-9-6(2)8-3-7(9)10(12)13/h3,5,11H,4H2,1-2H3

Molecular Formula

C7H11N3O3

HBD / HBA

1 / 4

回転可能結合数

2

重原子数

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

Secnidazole is a 5-nitroimidazole antiprotozoal and antibacterial agent with a longer half-life than metronidazole, approved for single-dose treatment of bacterial vaginosis and trichomoniasis. Its active nitroimidazole moiety is reduced intracellularly to cytotoxic intermediates that disrupt DNA integrity in anaerobic bacteria and parasites. Single-dose oral administration improves adherence compared to multi-day regimens.

Yes, Secnidazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL498847. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71815. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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構造

クイックデータ

分子式: C7H11N3O3
同義語: 1

外部リンク

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.