Segesterone Acetate
Segesterone acetate is a synthetic 19-nor progestin with high progestogenic and anti-estrogenic activity, used as the progestogen component in a contraceptive vaginal system (Annovera) that provides up to one year of contraceptive protection. It acts on progesterone receptors to suppress ovulation, thicken cervical mucus, and alter the endometrium, preventing fertilization and implantation. Its unique ring delivery system provides controlled, continuous release over 13 menstrual cycles.
分子量
370.5000 g/mol
LogP
2.90
TPSA
60.40 Ų
リピンスキーの五則
適合
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
C=C1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]2(C)[C@@]1(OC(C)=O)C(C)=O
InChI
InChI=1S/C23H30O4/c1-13-11-21-20-7-5-16-12-17(26)6-8-18(16)19(20)9-10-22(21,4)23(13,14(2)24)27-15(3)25/h12,18-21H,1,5-11H2,2-4H3/t18-,19+,20+,21-,22-,23-/m0/s1
Molecular Formula
C23H30O4
HBD / HBA
- / 4
回転可能結合数
3
重原子数
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Segesterone acetate is a synthetic 19-nor progestin with high progestogenic and anti-estrogenic activity, used as the progestogen component in a contraceptive vaginal system (Annovera) that provides up to one year of contraceptive protection. It acts on progesterone receptors to suppress ovulation, thicken cervical mucus, and alter the endometrium, preventing fertilization and implantation. Its unique ring delivery system provides controlled, continuous release over 13 menstrual cycles.
Yes, Segesterone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3707377. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 108059. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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