Sodium Fluoride F 18
Sodium fluoride F-18 is a bone-seeking positron emission tomography (PET) imaging agent in which fluorine-18 replaces hydroxyl groups in hydroxyapatite at sites of active bone turnover, used to detect osteoblastic bone metastases and primary bone tumors in prostate and non-small cell lung cancer. The high extraction efficiency of fluoride by bone and favorable PET imaging characteristics of F-18 provide superior sensitivity and resolution compared to conventional bone scintigraphy. It allows whole-body bone imaging for staging and response assessment.
分子量
40.9907 g/mol
TPSA
0.00 Ų
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
[18F-].[Na+]
InChI
InChI=1S/FH.Na/h1H;/q;+1/p-1/i1-1;
Molecular Formula
FNa
HBD / HBA
- / 1
回転可能結合数
0
重原子数
2
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Sodium fluoride F-18 is a bone-seeking positron emission tomography (PET) imaging agent in which fluorine-18 replaces hydroxyl groups in hydroxyapatite at sites of active bone turnover, used to detect osteoblastic bone metastases and primary bone tumors in prostate and non-small cell lung cancer. The high extraction efficiency of fluoride by bone and favorable PET imaging characteristics of F-18 provide superior sensitivity and resolution compared to conventional bone scintigraphy. It allows whole-body bone imaging for staging and response assessment.
Yes, Sodium Fluoride F 18 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200744. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23690531. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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