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Sulconazole

CHEMBL1221 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
397.7 g/mol
LogP
6.1
Phase
4

Sulconazole is a broad-spectrum imidazole antifungal agent used topically for the treatment of dermatophyte infections including tinea pedis, tinea corporis, tinea cruris, and tinea versicolor. It inhibits fungal lanosterol 14-alpha demethylase, a cytochrome P450 enzyme essential for ergosterol biosynthesis, disrupting fungal cell membrane integrity and function. It also has some anti-gram-positive bacterial activity.

分子量

397.7000 g/mol

LogP

6.10

TPSA

43.10 Ų

リピンスキーの五則

適合

作用機序

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

2D構造

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Clc1ccc(CSC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C18H15Cl3N2S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H15Cl3N2S

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
回転可能結合数

                        
6

                    

                    
                    
                    

                        
重原子数

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
よくある質問

                

                    
                    

                        
                        

                            
Sulconazole is a broad-spectrum imidazole antifungal agent used topically for the treatment of dermatophyte infections including tinea pedis, tinea corporis, tinea cruris, and tinea versicolor. It inhibits fungal lanosterol 14-alpha demethylase, a cytochrome P450 enzyme essential for ergosterol biosynthesis, disrupting fungal cell membrane integrity and function. It also has some anti-gram-positive bacterial activity.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Sulconazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1221.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5318.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
医学的免責事項

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.