Sunitinib
A multi-targeted tyrosine kinase inhibitor that blocks several receptors on tumor cells and their blood supply simultaneously, used for kidney cancer, gastrointestinal stromal tumors, and certain pancreatic tumors. By cutting off the tumor's blood supply and directly inhibiting cancer cell growth signals, it helps slow or stop tumor progression.
分子量
398.5000 g/mol
LogP
2.60
TPSA
77.20 Ų
リピンスキーの五則
適合
治療領域
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D構造
Cite this structure
Embed this structure
SMILES
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C
InChI
InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
Molecular Formula
C22H27FN4O2
HBD / HBA
3 / 4
回転可能結合数
7
重原子数
29
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
A multi-targeted tyrosine kinase inhibitor that blocks several receptors on tumor cells and their blood supply simultaneously, used for kidney cancer, gastrointestinal stromal tumors, and certain pancreatic tumors. By cutting off the tumor's blood supply and directly inhibiting cancer cell growth signals, it helps slow or stop tumor progression.
Yes, Sunitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL535. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5329102. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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