Technetium Tc 99M Disofenin

CHEMBL1200923 Phase 4 承認済み Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
449.3 g/mol
LogP
Phase
4

Technetium Tc 99m disofenin is a hepatobiliary iminodiacetic acid radiopharmaceutical used for HIDA scintigraphy to evaluate hepatobiliary function, gallbladder emptying, and biliary tract anatomy. See technetium-disofenin for complete pharmacological details. It provides functional imaging of hepatocyte uptake and biliary excretion dynamics.

分子量

449.3000 g/mol

TPSA

107.00 Ų

作用機序

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

SMILES

CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)CN(CC(=O)O)CC(=O)O.[99Tc]

InChI

InChI=1S/C18H26N2O5.Tc/c1-11(2)13-6-5-7-14(12(3)4)18(13)19-15(21)8-20(9-16(22)23)10-17(24)25;/h5-7,11-12H,8-10H2,1-4H3,(H,19,21)(H,22,23)(H,24,25);/i;1+1

Molecular Formula

C18H26N2O5Tc

HBD / HBA

3 / 6

回転可能結合数

9

重原子数

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

Technetium Tc 99m disofenin is a hepatobiliary iminodiacetic acid radiopharmaceutical used for HIDA scintigraphy to evaluate hepatobiliary function, gallbladder emptying, and biliary tract anatomy. See technetium-disofenin for complete pharmacological details. It provides functional imaging of hepatocyte uptake and biliary excretion dynamics.

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Yes, Technetium Tc 99M Disofenin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200923. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11430828. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.