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Technetium Tc 99M Exametazime

CHEMBL2107074 Phase 4 承認済み Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
384.3 g/mol
LogP
—
Phase
4

Technetium Tc 99m exametazime (99mTc-HMPAO) is a lipophilic radiopharmaceutical used for cerebral perfusion SPECT imaging and radiolabeling of leukocytes for infection/inflammation detection. See technetium-exametazime for complete pharmacological details. It is widely used in nuclear medicine for neurological and inflammatory disease evaluation.

分子量

384.2700 g/mol

TPSA

87.10 Ų

作用機序

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

機序

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

SMILES

C[C@H](/C(=N/O)/C)[N-]CC(C)(C)C[N-][C@H](C)/C(=N/[O-])/C.O=[99Tc+3]

InChI

InChI=1S/C13H26N4O2.O.Tc/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19;;/h9-10,18-19H,7-8H2,1-6H3;;/q-2;;+3/p-1/b16-11+,17-12+;;/t9-,10-;;/m1../s1/i;;1+1

Molecular Formula

C13H25N4O3Tc

HBD / HBA

1 / 7

回転可能結合数

8

重原子数

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

よくある質問

Technetium Tc 99m exametazime (99mTc-HMPAO) is a lipophilic radiopharmaceutical used for cerebral perfusion SPECT imaging and radiolabeling of leukocytes for infection/inflammation detection. See technetium-exametazime for complete pharmacological details. It is widely used in nuclear medicine for neurological and inflammatory disease evaluation.

Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.

Yes, Technetium Tc 99M Exametazime is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107074. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11954234. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

医学的免責事項

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.