Technetium Tc 99M Mebrofenin
Technetium Tc 99m mebrofenin is a high-efficiency hepatobiliary radiopharmaceutical with superior hepatic extraction for HIDA scintigraphy, particularly valuable in jaundiced patients. See technetium-mebrofenin for complete pharmacological details. It provides high-contrast hepatobiliary imaging for functional and anatomical assessment of the biliary system.
分子量
869.3000 g/mol
TPSA
225.00 Ų
作用機序
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
SMILES
CC1=CC(=C(C(=C1NC(=O)CN(CC(=O)[O-])CC(=O)[O-])C)Br)C.CC1=CC(=C(C(=C1NC(=O)CN(CC(=O)[O-])CC(=O)[O-])C)Br)C.[99Tc+4]
InChI
InChI=1S/2C15H19BrN2O5.Tc/c2*1-8-4-9(2)15(10(3)14(8)16)17-11(19)5-18(6-12(20)21)7-13(22)23;/h2*4H,5-7H2,1-3H3,(H,17,19)(H,20,21)(H,22,23);/q;;+4/p-4/i;;1+1
Molecular Formula
C30H34Br2N4O10Tc
HBD / HBA
2 / 12
回転可能結合数
10
重原子数
47
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Technetium Tc 99m mebrofenin is a high-efficiency hepatobiliary radiopharmaceutical with superior hepatic extraction for HIDA scintigraphy, particularly valuable in jaundiced patients. See technetium-mebrofenin for complete pharmacological details. It provides high-contrast hepatobiliary imaging for functional and anatomical assessment of the biliary system.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Technetium Tc 99M Mebrofenin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200421. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 172866200. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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