Vaccinia Virus, Live Modified
Modified vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus created by serial passage in chicken embryo fibroblasts, producing a replication-incompetent virus used as a vaccine vector and smallpox vaccine. It is used as the basis for JYNNEOS/Imvamune, approved for smallpox and monkeypox prevention, and as a vaccine vector platform for HIV, tuberculosis, malaria, and other infectious diseases. Its attenuated nature provides improved safety compared to traditional vaccinia while maintaining strong immunogenicity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Modified vaccinia Ankara (MVA) is a highly attenuated strain of vaccinia virus created by serial passage in chicken embryo fibroblasts, producing a replication-incompetent virus used as a vaccine vector and smallpox vaccine. It is used as the basis for JYNNEOS/Imvamune, approved for smallpox and monkeypox prevention, and as a vaccine vector platform for HIV, tuberculosis, malaria, and other infectious diseases. Its attenuated nature provides improved safety compared to traditional vaccinia while maintaining strong immunogenicity.
Yes, Vaccinia Virus, Live Modified is an approved drug. It has reached clinical phase 4. It is classified as a Vaccine component.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6068373. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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