Xenon Xe-129, Hyperpolarized
Hyperpolarized xenon-129 is a nuclear spin-polarized form of 129Xe gas used in MRI to provide high-resolution imaging of pulmonary airspaces, airways, and gas exchange based on its unique NMR properties, particularly its sensitivity to the microenvironment of red blood cells and lung tissue. Unlike conventional contrast agents, it enables non-radioactive MRI-based assessment of regional ventilation, diffusion, and gas transfer function in lung diseases including COPD, asthma, and interstitial lung disease. Its hyperpolarized state provides a several-thousand-fold enhancement in MRI signal.
分子量
128.9048 g/mol
TPSA
0.00 Ų
作用機序
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
2D構造
Cite this structure
Embed this structure
SMILES
[129Xe]
InChI
InChI=1S/Xe/i1-2
Molecular Formula
Xe
HBD / HBA
- / -
回転可能結合数
0
重原子数
1
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Hyperpolarized xenon-129 is a nuclear spin-polarized form of 129Xe gas used in MRI to provide high-resolution imaging of pulmonary airspaces, airways, and gas exchange based on its unique NMR properties, particularly its sensitivity to the microenvironment of red blood cells and lung tissue. Unlike conventional contrast agents, it enables non-radioactive MRI-based assessment of regional ventilation, diffusion, and gas transfer function in lung diseases including COPD, asthma, and interstitial lung disease. Its hyperpolarized state provides a several-thousand-fold enhancement in MRI signal.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Xenon Xe-129, Hyperpolarized is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4594411. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 10290811. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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