Ytterbium Pentetate
Ytterbium pentetate (169Yb-DTPA) is a radioactive chelate complex where the rare earth element ytterbium-169 is conjugated to diethylenetriaminepentaacetic acid (DTPA), used as a radiopharmaceutical for cisternography and evaluation of cerebrospinal fluid dynamics by intrathecal injection. The radiolabeled complex distributes through the CSF spaces and can be imaged with gamma camera or SPECT to detect CSF leaks, communicating hydrocephalus, and CSF flow obstruction. Its gamma emission profile makes it suitable for nuclear medicine CSF imaging.
分子量
566.4000 g/mol
TPSA
196.00 Ų
作用機序
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
2D構造
Cite this structure
Embed this structure
SMILES
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O.[Yb]
InChI
InChI=1S/C14H23N3O10.Yb/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);
Molecular Formula
C14H23N3O10Yb
HBD / HBA
5 / 13
回転可能結合数
16
重原子数
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
よくある質問
Ytterbium pentetate (169Yb-DTPA) is a radioactive chelate complex where the rare earth element ytterbium-169 is conjugated to diethylenetriaminepentaacetic acid (DTPA), used as a radiopharmaceutical for cisternography and evaluation of cerebrospinal fluid dynamics by intrathecal injection. The radiolabeled complex distributes through the CSF spaces and can be imaged with gamma camera or SPECT to detect CSF leaks, communicating hydrocephalus, and CSF flow obstruction. Its gamma emission profile makes it suitable for nuclear medicine CSF imaging.
Contains a radioactive isotope that accumulates in specific tissues or organs, enabling detection and imaging of physiological processes or pathological conditions using nuclear medicine techniques.
Yes, Ytterbium Pentetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2219546. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 177638023. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="ytterbium-pentetate"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/ytterbium-pentetate/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/ytterbium-pentetate/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/ytterbium-pentetate/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="ytterbium-pentetate"></drugfyi-drug>