Acetaminophen vs Aspirin

## Acetaminophen vs Aspirin: Overview

This comparison examines the pharmacological differences between **Acetaminophen** and **Aspirin**.

## Mechanism of Action

**Acetaminophen**: Inhibits prostaglandin synthesis in the CNS and peripherally blocks pain impulse generation.

**Aspirin**: Irreversibly inhibits cyclooxygenase-1 and -2.

## Pharmacokinetics

**Half-life**: Acetaminophen — 1-4 hours; Aspirin — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Acetaminophen — C8H9NO2; Aspirin — C9H8O4.

**Molecular Weight**: Acetaminophen — 151.1630 g/mol; Aspirin — 180.1580 g/mol.

**Type**: Acetaminophen — Small molecule; Aspirin — Small molecule.