Acyclovir vs Hydroxychloroquine

## Acyclovir vs Hydroxychloroquine: Overview

This comparison examines the pharmacological differences between **Acyclovir** and **Hydroxychloroquine**.

## Mechanism of Action

**Acyclovir**: Guanosine analogue inhibiting viral DNA polymerase.

**Hydroxychloroquine**: Accumulates in lysosomes raising pH; inhibits toll-like receptor signaling.

## Pharmacokinetics

**Half-life**: Acyclovir — 2.5-3.3 hours; Hydroxychloroquine — 40-50 days.

## Chemical Properties

**Molecular Formula**: Acyclovir — C8H11N5O3; Hydroxychloroquine — C18H26ClN3O.

**Molecular Weight**: Acyclovir — 225.2050 g/mol; Hydroxychloroquine — 335.8720 g/mol.

**Type**: Acyclovir — Small molecule; Hydroxychloroquine — Small molecule.