Afatinib vs Enalapril

## Afatinib vs Enalapril: Overview

This comparison examines the pharmacological differences between **Afatinib** and **Enalapril**.

## Mechanism of Action

**Afatinib**: Irreversible covalent inhibitor of ErbB family (EGFR/HER1, HER2, HER4) tyrosine kinases.

**Enalapril**: Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

## Pharmacokinetics

**Half-life**: Afatinib — 37 hours; Enalapril — 11 hours.

## Chemical Properties

**Molecular Formula**: Afatinib — C24H25ClFN5O3; Enalapril — C20H28N2O5.

**Molecular Weight**: Afatinib — 485.9400 g/mol; Enalapril — 376.4470 g/mol.

**Type**: Afatinib — Small molecule; Enalapril — Small molecule.