Afatinib vs Vancomycin

## Afatinib vs Vancomycin: Overview

This comparison examines the pharmacological differences between **Afatinib** and **Vancomycin**.

## Mechanism of Action

**Afatinib**: Irreversible covalent inhibitor of ErbB family (EGFR/HER1, HER2, HER4) tyrosine kinases.

**Vancomycin**: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

## Pharmacokinetics

**Half-life**: Afatinib — 37 hours; Vancomycin — 4-6 hours.

## Chemical Properties

**Molecular Formula**: Afatinib — C24H25ClFN5O3; Vancomycin — C66H75Cl2N9O24.

**Molecular Weight**: Afatinib — 485.9400 g/mol; Vancomycin — 1449.2500 g/mol.

**Type**: Afatinib — Small molecule; Vancomycin — Small molecule.