Allopurinol vs Hydrochlorothiazide

## Allopurinol vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Allopurinol** and **Hydrochlorothiazide**.

## Mechanism of Action

**Allopurinol**: Xanthine oxidase inhibitor reducing uric acid production.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Allopurinol — 1-2 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Allopurinol — C5H4N4O; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Allopurinol — 136.1120 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Allopurinol — Small molecule; Hydrochlorothiazide — Small molecule.