Captopril vs Methylprednisolone

## Captopril vs Methylprednisolone: Overview

This comparison examines the pharmacological differences between **Captopril** and **Methylprednisolone**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Methylprednisolone**: Intermediate-acting synthetic glucocorticoid.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Methylprednisolone — 18-36 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Methylprednisolone — C22H30O5.

**Molecular Weight**: Captopril — 217.2850 g/mol; Methylprednisolone — 374.4710 g/mol.

**Type**: Captopril — Small molecule; Methylprednisolone — Small molecule.