Ciprofloxacin vs Trimethoprim

## Ciprofloxacin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Ciprofloxacin** and **Trimethoprim**.

## Mechanism of Action

**Ciprofloxacin**: Inhibits bacterial DNA gyrase and topoisomerase IV.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Ciprofloxacin — 4 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Ciprofloxacin — C17H18FN3O3; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Ciprofloxacin — 331.3460 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Ciprofloxacin — Small molecule; Trimethoprim — Small molecule.