Digoxin vs Spironolactone

## Digoxin vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Digoxin** and **Spironolactone**.

## Mechanism of Action

**Digoxin**: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Digoxin — 36-48 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Digoxin — C41H64O14; Spironolactone — C24H32O4S.

**Molecular Weight**: Digoxin — 780.9430 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Digoxin — Small molecule; Spironolactone — Small molecule.