Dulaglutide vs Exenatide

## Dulaglutide vs Exenatide: Overview

This comparison examines the pharmacological differences between **Dulaglutide** and **Exenatide**.

## Mechanism of Action

**Dulaglutide**: GLP-1 receptor agonist fused to Fc fragment; enhances glucose-dependent insulin secretion.

**Exenatide**: Synthetic exendin-4 GLP-1 receptor agonist enhancing glucose-dependent insulin secretion.

## Pharmacokinetics

**Half-life**: Dulaglutide — 5 days; Exenatide — 2.4 hours.

## Chemical Properties

**Type**: Dulaglutide — Protein; Exenatide — Protein.