Gabapentin vs Pregabalin

## Gabapentin vs Pregabalin: Overview

This comparison examines the pharmacological differences between **Gabapentin** and **Pregabalin**.

## Mechanism of Action

**Gabapentin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

**Pregabalin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

## Pharmacokinetics

**Half-life**: Gabapentin — 5-7 hours; Pregabalin — 6.3 hours.

## Chemical Properties

**Molecular Formula**: Gabapentin — C9H17NO2; Pregabalin — C8H17NO2.

**Molecular Weight**: Gabapentin — 171.2370 g/mol; Pregabalin — 159.2260 g/mol.

**Type**: Gabapentin — Small molecule; Pregabalin — Small molecule.