Gabapentin vs Sildenafil

## Gabapentin vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Gabapentin** and **Sildenafil**.

## Mechanism of Action

**Gabapentin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Gabapentin — 5-7 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Gabapentin — C9H17NO2; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Gabapentin — 171.2370 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Gabapentin — Small molecule; Sildenafil — Small molecule.