Gefitinib vs Imatinib

## Gefitinib vs Imatinib: Overview

This comparison examines the pharmacological differences between **Gefitinib** and **Imatinib**.

## Mechanism of Action

**Gefitinib**: Selective reversible inhibitor of EGFR tyrosine kinase.

**Imatinib**: Selective inhibitor of BCR-ABL, c-Kit, and PDGFR tyrosine kinases.

## Pharmacokinetics

**Half-life**: Gefitinib — 48 hours; Imatinib — 18 hours.

## Chemical Properties

**Molecular Formula**: Gefitinib — C22H24ClFN4O3; Imatinib — C29H31N7O.

**Molecular Weight**: Gefitinib — 446.9000 g/mol; Imatinib — 493.6030 g/mol.

**Type**: Gefitinib — Small molecule; Imatinib — Small molecule.