Gefitinib vs Ipilimumab

## Gefitinib vs Ipilimumab: Overview

This comparison examines the pharmacological differences between **Gefitinib** and **Ipilimumab**.

## Mechanism of Action

**Gefitinib**: Selective reversible inhibitor of EGFR tyrosine kinase.

**Ipilimumab**: Fully human anti-CTLA-4 IgG1 monoclonal antibody that blocks CTLA-4 inhibitory signaling.

## Pharmacokinetics

**Half-life**: Gefitinib — 48 hours; Ipilimumab — 14.7 days.

## Chemical Properties

**Molecular Formula**: Gefitinib — C22H24ClFN4O3; Ipilimumab — N/A.

**Molecular Weight**: Gefitinib — 446.9000 g/mol; Ipilimumab — N/A.

**Type**: Gefitinib — Small molecule; Ipilimumab — Antibody.