Phentolamine vs Sildenafil

## Phentolamine vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Phentolamine** and **Sildenafil**.

## Mechanism of Action

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Phentolamine — N/A; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Phentolamine — N/A; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Phentolamine — N/A; Sildenafil — 474.5800 g/mol.

**Type**: Phentolamine — Small molecule; Sildenafil — Small molecule.