Tofacitinib vs Warfarin

## Tofacitinib vs Warfarin: Overview

This comparison examines the pharmacological differences between **Tofacitinib** and **Warfarin**.

## Mechanism of Action

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

**Warfarin**: Inhibits vitamin K epoxide reductase complex.

## Pharmacokinetics

**Half-life**: Tofacitinib — 3.2 hours; Warfarin — 20-60 hours.

## Chemical Properties

**Molecular Formula**: Tofacitinib — C16H20N6O; Warfarin — C19H16O4.

**Molecular Weight**: Tofacitinib — 312.3700 g/mol; Warfarin — 308.3280 g/mol.

**Type**: Tofacitinib — Small molecule; Warfarin — Small molecule.