Bretylium Tosylate

CHEMBL1095292 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

414.4 g/mol

LogP

—

Phase

4

The tosylate salt of bretylium, an antiarrhythmic agent used historically in emergency management of ventricular fibrillation and tachycardia. It stabilizes the heart's electrical activity by depleting norepinephrine from nerve terminals. It is no longer commercially available in most countries.

분자량

414.4000 g/mol

TPSA

65.60 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

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SMILES

CC[N+](C)(C)Cc1ccccc1Br.Cc1ccc(S(=O)(=O)[O-])cc1

InChI

InChI=1S/C11H17BrN.C7H8O3S/c1-4-13(2,3)9-10-7-5-6-8-11(10)12;1-6-2-4-7(5-3-6)11(8,9)10/h5-8H,4,9H2,1-3H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

Molecular Formula

C18H24BrNO3S

HBD / HBA

- / 3

회전 가능 결합

3

무거운 원자

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

The tosylate salt of bretylium, an antiarrhythmic agent used historically in emergency management of ventricular fibrillation and tachycardia. It stabilizes the heart's electrical activity by depleting norepinephrine from nerve terminals. It is no longer commercially available in most countries.

Yes, Bretylium Tosylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1095292. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6100. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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구조

핵심 데이터

분자식: C18H24BrNO3S

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.