Ceftizoxime Sodium

CHEMBL1201019 Phase 4 승인됨 Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
405.4 g/mol
LogP
Phase
4

The sodium salt form of ceftizoxime, used intravenously for the treatment of serious infections including pelvic inflammatory disease and certain types of meningitis. It provides the same broad-spectrum coverage as the parent compound with good activity against anaerobes. Standard precautions regarding cephalosporin hypersensitivity apply.

분자량

405.4000 g/mol

TPSA

204.00 Ų

작용 기전

Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.

2D 구조

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SMILES

CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=CCS[C@H]12)c1csc(N)n1.[Na+]

InChI

InChI=1S/C13H13N5O5S2.Na/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18;/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22);/q;+1/p-1/b17-7-;/t8-,11-;/m1./s1

Molecular Formula

C13H12N5NaO5S2

HBD / HBA

2 / 10

회전 가능 결합

5

무거운 원자

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

The sodium salt form of ceftizoxime, used intravenously for the treatment of serious infections including pelvic inflammatory disease and certain types of meningitis. It provides the same broad-spectrum coverage as the parent compound with good activity against anaerobes. Standard precautions regarding cephalosporin hypersensitivity apply.

Disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting the final transpeptidation step of peptidoglycan synthesis. The resulting cell wall defects cause osmotic instability and bacteriolysis.

Yes, Ceftizoxime Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201019. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 23663938. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.