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Cenobamate

CHEMBL3989949 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
267.7 g/mol
LogP
1.5
Phase
4

An antiepileptic drug with a dual mechanism, reducing repetitive neuronal firing by blocking sodium channels and enhancing gamma-aminobutyric acid (GABA) activity through modulation of GABAA receptors. It is used as adjunctive therapy for focal-onset seizures in adults. Initiation must be gradual to minimize the risk of a serious multiorgan hypersensitivity reaction called drug reaction with eosinophilia and systemic symptoms (DRESS).

분자량

267.6700 g/mol

LogP

1.50

TPSA

95.90 Ų

리핀스키 5의 법칙

통과

치료 영역

Epilepsy

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
NC(=O)O[C@@H](Cn1ncnn1)c1ccccc1Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C10H10ClN5O2/c11-8-4-2-1-3-7(8)9(18-10(12)17)5-16-14-6-13-15-16/h1-4,6,9H,5H2,(H2,12,17)/t9-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H10ClN5O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 5

                    

                    
                    

                        
회전 가능 결합

                        
5

                    

                    
                    
                    

                        
무거운 원자

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
An antiepileptic drug with a dual mechanism, reducing repetitive neuronal firing by blocking sodium channels and enhancing gamma-aminobutyric acid (GABA) activity through modulation of GABAA receptors. It is used as adjunctive therapy for focal-onset seizures in adults. Initiation must be gradual to minimize the risk of a serious multiorgan hypersensitivity reaction called drug reaction with eosinophilia and systemic symptoms (DRESS).

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Cenobamate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3989949.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11962412.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.