Chlorhexidine Gluconate

CHEMBL4297088 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

897.8 g/mol

LogP

—

Phase

4

The gluconate salt form of chlorhexidine is the most commonly used formulation, available in varying concentrations for hand washing, surgical scrubs, wound care, and oral rinses. It provides sustained antimicrobial activity due to its ability to bind to skin proteins and be released over time. Rare but serious hypersensitivity reactions including anaphylaxis have been reported.

분자량

897.8000 g/mol

TPSA

454.00 Å²

치료 영역

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Cardiovascular Disease Age-Related Macular Degeneration Pain Management Ophthalmology Non-Small Cell Lung Cancer Chronic Obstructive Pulmonary Disease Alzheimer's Disease Schizophrenia Generalized Anxiety Disorder Infectious Disease Nephrology Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Atopic Dermatitis Chronic Pain Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

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SMILES

N=C(NCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1)NC(=N)Nc1ccc(Cl)cc1.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

InChI=1S/C22H30Cl2N10.2C6H12O7/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*7-1-2(8)3(9)4(10)5(11)6(12)13/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*2-5,7-11H,1H2,(H,12,13)/t;2*2-,3-,4+,5-/m.11/s1

Molecular Formula

C34H54Cl2N10O14

HBD / HBA

18 / 16

회전 가능 결합

23

무거운 원자

60

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

The gluconate salt form of chlorhexidine is the most commonly used formulation, available in varying concentrations for hand washing, surgical scrubs, wound care, and oral rinses. It provides sustained antimicrobial activity due to its ability to bind to skin proteins and be released over time. Rare but serious hypersensitivity reactions including anaphylaxis have been reported.

Yes, Chlorhexidine Gluconate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4297088. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9552081. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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구조

핵심 데이터

분자식: C34H54Cl2N10O14
동의어: 246

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.