Cisplatin
A platinum-based chemotherapy agent that forms crosslinks between DNA strands, disrupting DNA replication and transcription, leading to cancer cell death. It is a cornerstone of treatment for testicular, ovarian, bladder, lung, and head and neck cancers. Nephrotoxicity, ototoxicity, nausea, and peripheral neuropathy are major dose-limiting toxicities requiring vigorous supportive care.
분자량
300.0500 g/mol
TPSA
2.00 Ų
치료 영역
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
N.N.Cl[Pt]Cl
InChI
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
Molecular Formula
Cl2H6N2Pt
HBD / HBA
2 / 2
회전 가능 결합
0
무거운 원자
5
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
A platinum-based chemotherapy agent that forms crosslinks between DNA strands, disrupting DNA replication and transcription, leading to cancer cell death. It is a cornerstone of treatment for testicular, ovarian, bladder, lung, and head and neck cancers. Nephrotoxicity, ototoxicity, nausea, and peripheral neuropathy are major dose-limiting toxicities requiring vigorous supportive care.
Yes, Cisplatin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL11359. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5460033. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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