Dexamethasone Phosphoric Acid

CHEMBL1201302 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

472.4 g/mol

LogP

0.1

Phase

4

A phosphate ester form of dexamethasone, a potent corticosteroid used to reduce inflammation and suppress the immune system. It is converted in the body to active dexamethasone after administration.

분자량

472.4000 g/mol

LogP

0.10

TPSA

141.00 Å²

리핀스키 5의 법칙

통과

작용 기전

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

2D 구조

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SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)(O)O

InChI

InChI=1S/C22H30FO8P/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30)/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

Molecular Formula

C22H30FO8P

HBD / HBA

4 / 9

회전 가능 결합

4

무거운 원자

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

A phosphate ester form of dexamethasone, a potent corticosteroid used to reduce inflammation and suppress the immune system. It is converted in the body to active dexamethasone after administration.

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

Yes, Dexamethasone Phosphoric Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201302. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9400. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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구조

핵심 데이터

분자식: C22H30FO8P

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Dexamethasone Phosphoric Acid

작용 기전

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

자주 묻는 질문

References & Data Sources

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