Enasidenib
This oral medication works by blocking a mutated enzyme called IDH2 that drives the growth of certain leukemia cells. It helps abnormal cells mature into normal blood cells instead of continuing to divide uncontrollably.
분자량
473.4000 g/mol
LogP
3.50
TPSA
109.00 Ų
리핀스키 5의 법칙
통과
치료 영역
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
CC(C)(O)CNc1nc(Nc2ccnc(C(F)(F)F)c2)nc(-c2cccc(C(F)(F)F)n2)n1
InChI
InChI=1S/C19H17F6N7O/c1-17(2,33)9-27-15-30-14(11-4-3-5-12(29-11)18(20,21)22)31-16(32-15)28-10-6-7-26-13(8-10)19(23,24)25/h3-8,33H,9H2,1-2H3,(H2,26,27,28,30,31,32)
Molecular Formula
C19H17F6N7O
HBD / HBA
3 / 14
회전 가능 결합
6
무거운 원자
33
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
This oral medication works by blocking a mutated enzyme called IDH2 that drives the growth of certain leukemia cells. It helps abnormal cells mature into normal blood cells instead of continuing to divide uncontrollably.
Yes, Enasidenib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989908. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 89683805. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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