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Fludrocortisone Acetate

CHEMBL1201010 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
422.5 g/mol
LogP
1.7
Phase
4

This acetate salt form of fludrocortisone is a synthetic steroid hormone used to replace the mineralocorticoid function of the adrenal glands in patients with adrenal insufficiency. It helps maintain blood pressure and electrolyte balance by promoting sodium retention in the kidneys.

분자량

422.5000 g/mol

LogP

1.70

TPSA

101.00 Ų

리핀스키 5의 법칙

통과

치료 영역

Parkinson's Disease Melanoma Type 2 Diabetes Hypertension Heart Failure Prostate Cancer

작용 기전

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

                

                

                
                

                    
InChI

                    
InChI=1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C23H31FO6

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
회전 가능 결합

                        
4

                    

                    
                    
                    

                        
무거운 원자

                        
30

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
This acetate salt form of fludrocortisone is a synthetic steroid hormone used to replace the mineralocorticoid function of the adrenal glands in patients with adrenal insufficiency. It helps maintain blood pressure and electrolyte balance by promoting sodium retention in the kidneys.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Provides an essential mineral element required for numerous enzymatic reactions, structural proteins, and physiological processes. Supplementation addresses deficiency states.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Fludrocortisone Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201010.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 225609.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.