Isosorbide Dinitrate

CHEMBL6622 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

236.1 g/mol

LogP

1.3

Phase

4

This nitrate vasodilator is used to treat and prevent angina pectoris (chest pain) and to reduce the symptoms of heart failure. It works by releasing nitric oxide, which relaxes vascular smooth muscle and widens blood vessels, reducing the workload on the heart. Tolerance can develop with continuous use, so nitrate-free intervals are recommended.

분자량

236.1400 g/mol

LogP

1.30

TPSA

129.00 Å²

리핀스키 5의 법칙

통과

치료 영역

Glaucoma Cardiovascular Disease Osteoporosis Stroke Obesity Type 2 Diabetes Hypertension Atopic Dermatitis Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

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SMILES

O=[N+]([O-])O[C@H]1CO[C@H]2[C@@H]1OC[C@H]2O[N+](=O)[O-]

InChI

InChI=1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2/t3-,4+,5-,6-/m1/s1

Molecular Formula

C6H8N2O8

HBD / HBA

- / 8

회전 가능 결합

2

무거운 원자

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

This nitrate vasodilator is used to treat and prevent angina pectoris (chest pain) and to reduce the symptoms of heart failure. It works by releasing nitric oxide, which relaxes vascular smooth muscle and widens blood vessels, reducing the workload on the heart. Tolerance can develop with continuous use, so nitrate-free intervals are recommended.

Yes, Isosorbide Dinitrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6622. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6883. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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구조

핵심 데이터

분자식: C6H8N2O8
동의어: 4

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.