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Mebanazine

CHEMBL1909283 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
136.2 g/mol
LogP
0.9
Phase
4

This monoamine oxidase inhibitor (MAOI) was used as an antidepressant but was withdrawn from clinical use due to its potential for severe, potentially fatal interactions with certain foods and medications containing tyramine or other amines. MAOIs like mebanazine require strict dietary restrictions to prevent dangerous blood pressure crises.

분자량

136.1900 g/mol

LogP

0.90

TPSA

38.10 Ų

리핀스키 5의 법칙

통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(NN)c1ccccc1

                

                

                
                

                    
InChI

                    
InChI=1S/C8H12N2/c1-7(10-9)8-5-3-2-4-6-8/h2-7,10H,9H2,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H12N2

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
회전 가능 결합

                        
2

                    

                    
                    
                    

                        
무거운 원자

                        
10

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
This monoamine oxidase inhibitor (MAOI) was used as an antidepressant but was withdrawn from clinical use due to its potential for severe, potentially fatal interactions with certain foods and medications containing tyramine or other amines. MAOIs like mebanazine require strict dietary restrictions to prevent dangerous blood pressure crises.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Mebanazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1909283.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 6179.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.