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Melphalan

CHEMBL852 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
305.2 g/mol
LogP
-0.5
Phase
4

An alkylating chemotherapy agent used to treat multiple myeloma, ovarian cancer, and as part of high-dose conditioning regimens before stem cell transplantation, working by cross-linking DNA to prevent cancer cell division. It belongs to the nitrogen mustard class of chemotherapy drugs.

분자량

305.2000 g/mol

LogP

-0.50

TPSA

66.60 Ų

리핀스키 5의 법칙

통과

치료 영역

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Melanoma Multiple Sclerosis Lymphoma Breast Cancer Chronic Pain HIV/AIDS Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
N[C@@H](Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H18Cl2N2O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
회전 가능 결합

                        
8

                    

                    
                    
                    

                        
무거운 원자

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
An alkylating chemotherapy agent used to treat multiple myeloma, ovarian cancer, and as part of high-dose conditioning regimens before stem cell transplantation, working by cross-linking DNA to prevent cancer cell division. It belongs to the nitrogen mustard class of chemotherapy drugs.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Melphalan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL852.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 460612.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.