Polihexanide

CHEMBL2106939 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

— g/mol

LogP

—

Phase

4

Polihexanide (polyhexamethylene biguanide, PHMB) is a cationic polymeric biocide that disrupts bacterial cell membranes by binding to negatively charged phospholipids, increasing membrane permeability and causing cell lysis. It is used as an antiseptic and disinfectant in wound care, contact lens solutions, and surface disinfection, with a broad spectrum of activity against bacteria, fungi, and protozoa including Acanthamoeba.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

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SMILES

CCCCCCNC(=N)NC(=N)N

InChI

InChI=1S/C8H19N5/c1-2-3-4-5-6-12-8(11)13-7(9)10/h2-6H2,1H3,(H6,9,10,11,12,13)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Polihexanide (polyhexamethylene biguanide, PHMB) is a cationic polymeric biocide that disrupts bacterial cell membranes by binding to negatively charged phospholipids, increasing membrane permeability and causing cell lysis. It is used as an antiseptic and disinfectant in wound care, contact lens solutions, and surface disinfection, with a broad spectrum of activity against bacteria, fungi, and protozoa including Acanthamoeba.

Yes, Polihexanide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2106939. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

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핵심 데이터

동의어: 3

외부 링크

ChEMBL CHEMBL2106939

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.