Prussian Blue Insoluble

CHEMBL2096629 Phase 4 승인됨 Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
859.2 g/mol
LogP
Phase
4

Prussian blue (insoluble ferric hexacyanoferrate) is an ion-exchange compound that binds radioactive cesium-137 and thallium ions with high affinity within the gastrointestinal tract, preventing their absorption and reabsorption, thereby accelerating their elimination via fecal excretion. It is approved as an antidote for internal contamination with radioactive cesium-137 and non-radioactive thallium, significantly reducing their biological half-lives.

분자량

859.2000 g/mol

TPSA

428.00 Ų

치료 영역

작용 기전

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

기전

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

SMILES

[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+2].[Fe+2].[Fe+2].[Fe+3].[Fe+3].[Fe+3].[Fe+3]

InChI

InChI=1S/18CN.7Fe/c18*1-2;;;;;;;/q18*-1;3*+2;4*+3

Molecular Formula

C18Fe7N18

HBD / HBA

- / 36

회전 가능 결합

0

무거운 원자

43

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Prussian blue (insoluble ferric hexacyanoferrate) is an ion-exchange compound that binds radioactive cesium-137 and thallium ions with high affinity within the gastrointestinal tract, preventing their absorption and reabsorption, thereby accelerating their elimination via fecal excretion. It is approved as an antidote for internal contamination with radioactive cesium-137 and non-radioactive thallium, significantly reducing their biological half-lives.

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

Yes, Prussian Blue Insoluble is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2096629. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 2724251. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.