Quinethazone

CHEMBL1532 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

289.7 g/mol

LogP

1.2

Phase

4

Quinethazone is a quinazoline sulfonamide diuretic structurally related to the thiazide diuretics that inhibits the sodium-chloride cotransporter (NCC) in the distal convoluted tubule of the kidney, reducing sodium and water reabsorption to produce diuresis and antihypertensive effects. It was used for the treatment of hypertension and edematous conditions.

분자량

289.7400 g/mol

LogP

1.20

TPSA

110.00 Å²

리핀스키 5의 법칙

통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

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SMILES

CCC1NC(=O)c2cc(S(N)(=O)=O)c(Cl)cc2N1

InChI

InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17)

Molecular Formula

C10H12ClN3O3S

HBD / HBA

3 / 5

회전 가능 결합

2

무거운 원자

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Quinethazone is a quinazoline sulfonamide diuretic structurally related to the thiazide diuretics that inhibits the sodium-chloride cotransporter (NCC) in the distal convoluted tubule of the kidney, reducing sodium and water reabsorption to produce diuresis and antihypertensive effects. It was used for the treatment of hypertension and edematous conditions.

Yes, Quinethazone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1532. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6307. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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분자식: C10H12ClN3O3S

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.