Rescinnamine

CHEMBL1668 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

634.7 g/mol

LogP

4.5

Phase

4

Rescinnamine is a Rauwolfia alkaloid antihypertensive agent that depletes catecholamine neurotransmitters from sympathetic nerve terminals and the adrenal medulla by interfering with vesicular monoamine transporter (VMAT) uptake, reducing peripheral vascular resistance and blood pressure. It was used for the treatment of mild to moderate hypertension, though it has been largely superseded by newer antihypertensive drug classes.

분자량

634.7000 g/mol

LogP

4.50

TPSA

118.00 Å²

리핀스키 5의 법칙

통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

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SMILES

COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)/C=C/c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC

InChI

InChI=1S/C35H42N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h7-10,13-14,16,20,24,26,29,31,34,36H,11-12,15,17-18H2,1-6H3/b10-7+/t20-,24+,26-,29-,31+,34+/m1/s1

Molecular Formula

C35H42N2O9

HBD / HBA

1 / 10

회전 가능 결합

11

무거운 원자

46

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

Rescinnamine is a Rauwolfia alkaloid antihypertensive agent that depletes catecholamine neurotransmitters from sympathetic nerve terminals and the adrenal medulla by interfering with vesicular monoamine transporter (VMAT) uptake, reducing peripheral vascular resistance and blood pressure. It was used for the treatment of mild to moderate hypertension, though it has been largely superseded by newer antihypertensive drug classes.

Yes, Rescinnamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1668. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5280954. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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구조

핵심 데이터

분자식: C35H42N2O9

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.