Rimantadine
Rimantadine is an adamantane antiviral agent structurally related to amantadine that inhibits the M2 ion channel of influenza A virus, blocking the hydrogen ion influx required for viral uncoating and preventing release of viral RNA into the host cell cytoplasm. It is used for prophylaxis and treatment of influenza A infections, though widespread resistance among circulating influenza A strains has significantly limited its clinical utility.
분자량
179.3000 g/mol
LogP
2.60
TPSA
26.00 Ų
리핀스키 5의 법칙
통과
치료 영역
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D 구조
Cite this structure
Embed this structure
SMILES
CC(N)C12CC3CC(CC(C3)C1)C2
InChI
InChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3
Molecular Formula
C12H21N
HBD / HBA
1 / 1
회전 가능 결합
1
무거운 원자
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
자주 묻는 질문
Rimantadine is an adamantane antiviral agent structurally related to amantadine that inhibits the M2 ion channel of influenza A virus, blocking the hydrogen ion influx required for viral uncoating and preventing release of viral RNA into the host cell cytoplasm. It is used for prophylaxis and treatment of influenza A infections, though widespread resistance among circulating influenza A strains has significantly limited its clinical utility.
Yes, Rimantadine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL959. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5071. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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