Vardenafil

CHEMBL1520 Phase 4 승인됨 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

488.6 g/mol

LogP

2.5

Phase

4

This PDE5 inhibitor is used to treat erectile dysfunction in men by relaxing the smooth muscle in the penis and increasing blood flow to enable an erection when sexually stimulated. It works within about an hour of taking it and lasts for four to five hours. It must not be taken with nitrate medications (used for chest pain) due to the risk of a potentially life-threatening drop in blood pressure.

분자량

488.6000 g/mol

LogP

2.50

TPSA

118.00 Å²

리핀스키 5의 법칙

통과

치료 영역

Benign Prostatic Hyperplasia Type 2 Diabetes Hypertension HIV/AIDS

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

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SMILES

CCCc1nc(C)c2c(=O)nc(-c3cc(S(=O)(=O)N4CCN(CC)CC4)ccc3OCC)[nH]n12

InChI

InChI=1S/C23H32N6O4S/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30)

Molecular Formula

C23H32N6O4S

HBD / HBA

1 / 8

회전 가능 결합

8

무거운 원자

34

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

자주 묻는 질문

This PDE5 inhibitor is used to treat erectile dysfunction in men by relaxing the smooth muscle in the penis and increasing blood flow to enable an erection when sexually stimulated. It works within about an hour of taking it and lasts for four to five hours. It must not be taken with nitrate medications (used for chest pain) due to the risk of a potentially life-threatening drop in blood pressure.

Yes, Vardenafil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1520. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135400189. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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구조

핵심 데이터

분자식: C23H32N6O4S
동의어: 2

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의학적 면책조항

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.