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Vasopressin

CHEMBL373742 Phase 4 승인됨 Protein
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Vasopressin (antidiuretic hormone, ADH) is an endogenous nonapeptide synthesized in the hypothalamus that acts on V1 receptors in vascular smooth muscle to cause vasoconstriction and on V2 receptors in renal collecting ducts to promote water reabsorption and urine concentration. Pharmacologically, it is used for vasodilatory shock (septic shock, post-cardiac surgery vasodilation) as a vasopressor and for diabetes insipidus due to ADH deficiency. Its vasopressor properties are exploited in resuscitation protocols and gastrointestinal bleeding.

치료 영역

Benign Prostatic Hyperplasia Cardiovascular Disease Pain Management Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Chronic Kidney Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Hypertension Major Depressive Disorder Breast Cancer Chronic Pain Hepatitis C Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O

                

                

                
                

                    
InChI

                    
InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1

                

                

                

                    
                    

                        
HBD / HBA

                        
- / -

                    

                    
                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
Vasopressin (antidiuretic hormone, ADH) is an endogenous nonapeptide synthesized in the hypothalamus that acts on V1 receptors in vascular smooth muscle to cause vasoconstriction and on V2 receptors in renal collecting ducts to promote water reabsorption and urine concentration. Pharmacologically, it is used for vasodilatory shock (septic shock, post-cardiac surgery vasodilation) as a vasopressor and for diabetes insipidus due to ADH deficiency. Its vasopressor properties are exploited in resuscitation protocols and gastrointestinal bleeding.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Vasopressin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL373742.
                Open-access bioactivity database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.