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Zomepirac

CHEMBL19490 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
291.7 g/mol
LogP
2.8
Phase
4

Zomepirac is a nonsteroidal anti-inflammatory drug (NSAID) and analgesic that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis to produce analgesic and anti-inflammatory effects. It was used for moderate to severe pain management but was withdrawn from the market due to serious anaphylactic reactions occurring particularly in aspirin-sensitive patients. It was notable for its potent analgesic effects comparable to opioids for some pain types.

분자량

291.7300 g/mol

LogP

2.80

TPSA

59.30 Ų

리핀스키 5의 법칙

통과

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

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SMILES

                    
Cc1cc(CC(=O)O)n(C)c1C(=O)c1ccc(Cl)cc1

                

                

                
                

                    
InChI

                    
InChI=1S/C15H14ClNO3/c1-9-7-12(8-13(18)19)17(2)14(9)15(20)10-3-5-11(16)6-4-10/h3-7H,8H2,1-2H3,(H,18,19)

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H14ClNO3

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
회전 가능 결합

                        
4

                    

                    
                    
                    

                        
무거운 원자

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
Zomepirac is a nonsteroidal anti-inflammatory drug (NSAID) and analgesic that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis to produce analgesic and anti-inflammatory effects. It was used for moderate to severe pain management but was withdrawn from the market due to serious anaphylactic reactions occurring particularly in aspirin-sensitive patients. It was notable for its potent analgesic effects comparable to opioids for some pain types.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Zomepirac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL19490.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5733.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.